84-3536-82 [取扱停止]HMG2 (High-mobility Group Box 2, High Mobility Group Protein B2, High Mobility Group Protein 2, HMG2, HMG-2, HMGB2) (PE) 200ul H6202-20D-PE
84-3536-82 [取扱停止]HMG2 (High-mobility Group Box 2, High Mobility Group Protein B2, High Mobility Group Protein 2, HMG2, HMG-2, HMGB2) (PE) 200ul H6202-20D-PE
HMGB2 is a member of the non-histone chromosomal high mobility group protein family.
The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells.
In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles.
These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility.
This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Western Blot: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Specificity:Recognizes human HMGB2.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide selected from the Center region of human HMGB2 (KLH).