84-3489-69　［取扱停止］MYO5B (Unconventional Myosin-Vb, MYO5B, KIAA1119) (Biotin) 100ul　302582-Biotin

特徴

• May be involved in vesicular trafficking via its association with the CART complex.
• The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
• Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane.
• Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells.
• Together with RAB11A and RAB8A participates in epithelial cell polarization.
• Together with RAB25 regulates transcytosis.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.