ACR is the major proteinase present in the acrosome of mature spermatozoa.
It is a typical serine proteinase with trypsin-like specificity.
It is stored in the acrosome in its precursor form, proacrosin.
The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum.
The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis.
In humans proacrosin first appears in the haploid spermatids.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity：Recognizes human ACR
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392~421 amino acids from the C-terminal region of human ACR.
