84-3477-66　［取扱停止］ARGBP2, NT (Sorbin and SH3 Domain-containing Protein 2, Arg/Abl-interacting Protein 2, ArgBP2, Sorbin, KIAA0777, SORBS2) (Biotin) 200ul　A3340-02-Biotin

特徴

• Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases.
• They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins.
• ARGBP2 is the sorbin and SH3 domain containing 2 protein.
• It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins.
• The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.