84-3473-34　［取扱停止］WWOX (Phospho-Tyr33) (APC) 100ul　302845-APC

特徴

• This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family.
• This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene.
• Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer.
• Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12.
• Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein.
• Alternative splicing results in multiple transcript variants.
• [provided by RefSeq, May 2014].
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000Immunohistochemistry: 1:50~100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: APC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.