84-3465-86　［取扱停止］LGR5, loop2 (LGR5, GPR49, GPR67, Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38) (APC) 200ul　037760-APC

特徴

• LGR5/GPR49 is an orphan receptor.
• It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
• Stem cell marker of the intestinal epithelium and the hair follicle.
• Target gene of Wnt signaling.
• Expressed in skeletal muscle, placenta, spinal cord, and various region of brain.
• Expressed at the base of crypts in colonic and small mucosa stem cells.
• In premalignant cancer expression is not restricted to the cript base.
• Overexpressed in cancers of the ovary, colon and liver.
• Applications:Suitable for use in Immunofluorescence, Flow Cytometry (Not Tested), Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: APC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.