84-3453-87　［取扱停止］TAS2R43 (Taste Receptor Type 2 Member 43, T2R43, Taste Receptor Type 2 Member 52, T2R52, TAS2R43) (AP) 200ul　302787-AP

特徴

• Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.
• Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
• Activated by the sulfonyl amide sweeteners saccharin and acesulfame K.
• In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
• May acts as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.