Transcriptional repressor of genes that require a bHLH protein for their transcription.
May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity).
Binds DNA on N-boxenopus motifs: 5'-CACNAG-3' with high affinity and on E-boxenopus motifs: 5'-CANNTG-3' with low affinity.
May play a role in a functional FA core complexenopus response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complexenopus proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Specificity：Recognizes mouse Hes1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo
Immunogen：KLH conjugated synthetic peptide corresponding to aa102-137 at the Central region of Mouse Hes1. Species sequence homology: xenopus, bovine, human, rat
