ACR is the major proteinase present in the acrosome of mature spermatozoa.
It is a typical serine proteinase with trypsin-like specificity.
It is stored in the acrosome in its precursor form, proacrosin.
The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum.
The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis.
In humans proacrosin first appears in the haploid spermatids.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry (Not Tested), ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Specificity：Recognizes human ACR
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106~135 amino acids from the Center region of human ACR.
