FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking.
This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin.
The protein is highly similar to the FK506-binding protein 1A.
Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
Applications:Suitable for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Other applications not tested.
Recommended Dilution:Immunocytochemistry/Immunofluorescence: 1:10-1:50Immunohistochemistry: 1:10-1:50Western Blot: 1:1,000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Specificity:Recognizes human FKBP1B. Species Crossreactivity: mouse.
Isotype:IgG
Calc Applications Abbrev:IC IF IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide corresponding to a fragment of amino acids located between corresponding to a portion of amino acids within aa16-46 in the N-terminal region of human FKBP1B.