84-3435-30　ST5 (DENN Domain Containing Protein 2B, DENN Domain-containing Protein 2B, DENN/MADD Domain Containing 2B, DENND2B, HeLa Tumor Suppression 1, HTS1, P126, ST 5, Suppression of Tumorigenicity 5, Suppression of Tumorigenicity 5 Protein) 100ug　303645

特徴

• Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene.
• This gene is mapped to 11p15.4.
• The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins.
• This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells.
• Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.