Ras-related protein Rab-9A, also called RAB9, is a protein that in humans is encoded by the RAB9A gene.
This gene is mapped to Xp22.2.
RAB9 has been localized to components of the endocytic/exocytic pathway and has been implicated in recycling of membrane receptors.
It has been found that downregulation of RAB9A gene expression in HeLa cells induced severe cell vacuolation.
RAB9A GTPase is directly bound by TIP47 in its active, GTP-bound conformation.
Moreover, RAB9A increases the affinity of TIP47 for its cargo.
This gene may involved in the transport of proteins between the endosomes and the trans Golgi network.
RAB9A has been shown to interact with RABEPK and TIP47.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human Rab9. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa178-193, RSDHLIQTDTVNLHRK, from human Rab9 at C-terminus, identical to the related rat sequence, and different from the related mouse sequence by 1aa.
