84-3434-62 Rab3A, CT (Rab 3A, RAB 3A Member RAS Oncogene Family, Rab3a, RAB3A Member RAS Oncogene Family, RAB3A_HUMAN, RAS Associated Protein RAB 3A, RAS Associated Protein RAB3A, Ras Related Protein Rab 3A, Ras Related Protein Rab3A, Ras-related Protein Rab-3A) 100ug 303566
84-3434-62 Rab3A, CT (Rab 3A, RAB 3A Member RAS Oncogene Family, Rab3a, RAB3A Member RAS Oncogene Family, RAB3A_HUMAN, RAS Associated Protein RAB 3A, RAS Associated Protein RAB3A, Ras Related Protein Rab 3A, Ras Related Protein Rab3A, Ras-related Protein Rab-3A) 100ug 303566
Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene.
This gene is mapped to 19p13.11.
Synapsin I stimulated the RAB3A cycle by increasing GTP binding, GTPase activity, and RAB3A recruitment to the synaptic vesicle membrane.
Conversely, RAB3A inhibited synapsin I binding to actin and synapsin I-induced synaptic vesicle clustering.
It has been found that RAB3A was necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons.
In addition to that, RAB3A has been found to regulate a late step in synaptic vesicle fusion.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes human Rab3A. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa192-220, DTADPAVTGAKQGPQLSDQQVPPHQDCAC, from human Rab3A at C-terminus, different from the related mouse and rat sequences by 2aa.