Prospero homeobox protein 1, also called PROX1 is a protein that in humans is encoded by the PROX1 gene.
This gene is mapped to 1q32.3.
The protein encoded by this gene is a member of the homeobox transcription factor family.
Members of this family contain a homeobox domain that consists of a 60aa helix-turn-helix structure that binds DNA and RNA.
The protein encoded by this gene is conserved across vertebrates and may play an essential role during development.
Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes human PROX1. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa346-359, KHLAETLKQELNTA, from the middle region of human PROX1, identical to the related mouse and rat sequences.