84-3434-36　PKC delta (CVID9, Kinase PKC delta, KPCD, KPCD_HUMAN, MAY 1, MAY1, NPKC delta, NPKC-delta, PCKd, PKC d, PKCd, PKCD, PKCdelta, PRKC D, PRKC delta, Prkcd, Protein Kinase C delta, Protein Kinase C delta Type, Protein Kinase C delta VIII, Protein Kinase C delta, Tyrosine Protein Kinase PRKCD) 100ug　303536

特徴

• Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene.
• The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis.
• This gene is mapped to 3p21.1.
• Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types.
• PRKCD is also regulated by phosphorylation on various tyrosine residues including Y311 (by SRC).
• It has been showed that PRKCD phosphorylates NLRC4 and that this phosphorylation is critical for inflammasome assembly.
• It is also a part of a noncanonical WNT signaling cascade.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.