The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems.
An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing.
These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI.
Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human NRG1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human NRG1 expressed in E. coli. (Position: S2-K241). Species sequence homology: rat (94%)
Shelf Life：1year
Swiss Prot Number：Q02297
EU Commodity Code：30021010
商品名：NRG1 (Acetylcholine Receptor Inducing Activity, Acetylcholine Receptor-inducing Activity, Acetylcholine Receptor-inducing Activity, CHICK, Homolog of, ARIA, Breast Cancer Cell Differentiation Factor p45, ERBB2 p185 Activator, GGF 2, GGF, GGF2, Glial Growth Factor, Heregulin alpha, Heregulin, Heregulin, alpha (45kD, ERBB2 p185-activator), HGL, HRG 1, HRG, HRG1, HRGA, MST131, NDF, Neu Differentiation Factor, Neuregulin 1, Neuregulin 1 Type IV beta 1a, Neuregulin 1 Type IV beta 3, Neuregulin-1, Neuregulin1, NRG 1, Nrg1, NRG1-IT2, NRG1_HUMAN, Pro Neuregulin 1, Pro NRG1, Pro-neuregulin-1, Membrane-bound Isoform, Pro-NRG1, Proneuregulin 1, ProNRG1, Sensory and Motor Neuron Derived Factor, Sensory and Motor Neuron-derived Factor, SMDF) 100ug
