The N-methyl-D-aspartate receptor 2B (NMDAR2B), also names as GRIN2B.
The sequence of the predicted 1,484aa human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively.
Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically.
Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100Hz.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human NMDAR2B. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human NMDAR2B expressed in E. coli. (Position: N1076-D1332). Species sequence homology: mouse (98%) and rat (97%)
Shelf Life：1year
Swiss Prot Number：Q13224
EU Commodity Code：30021010
商品名：NMDAR2B (Glutamate [NMDA] Receptor Subunit epsilon 2, Glutamate [NMDA] Receptor Subunit epsilon-2, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B, Glutamate Receptor Ionotropic NMDA2B, Glutamate Receptor Subunit epsilon 2, Glutamate Receptor, Ionotropic, NMDA2B (epsilon 2), GRIN 2B, GRIN2B, HNR 3, HNR3, N Methyl D Asparate Receptor Channel Subunit epsilon 2, N Methyl D Aspartate Receptor Channel Subunit Epsilon 2, N Methyl D Aspartate Receptor Subtype 2B, N Methyl D Aspartate Receptor Subunit 3, N-methyl D-aspartate Receptor Subtype 2B, N-methyl-D-aspartate Receptor Subunit 3, NMDA NR2B, NMDA R2B, Nmdar2b, NMDE2, NMDE2_HUMAN, NME2, NR2B, NR3) 100ug
![NMDAR2B (Glutamate [NMDA] Receptor Subunit epsilon 2, Glutamate [NMDA] Receptor Subunit epsilon-2, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B, Glutamate Receptor Ionotropic NMDA2B, Glutamate Receptor Subunit epsilon 2, Glutamate Receptor, Ionotropic, NMDA2B (epsilon 2), GRIN 2B, GRIN2B, HNR 3, HNR3, N Methyl D Asparate R ...](https://aimg.as-1.co.jp/c/84/3433/91/85133520.jpg)