Transcription factor p65, also known as NFKB3 or NF-kB p65, is a protein encoded by the RELA gene.
NFKB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system.
Phosphorylation and acetylation of NFKB3 are crucial post-translational modifications required for NFKB activation.
It has also been shown to modulate immune responses, and activation of NFKB3 is positively associated with multiple types of cancer.
In addition to that, NFKB3 antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes mouse NF-kB p65. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to mouse NF-kB p65 expressed in E. coli. (Position: D291-Q479). Species sequence homology: human (77%)
Shelf Life：1year
Swiss Prot Number：Q04207
EU Commodity Code：30021010
商品名：NF-kB, p65 (Avian Reticuloendotheliosis Viral (V Rel) Oncogene Homolog A, NF kappa B p65delta3, NFKB 3, NFKB3, Nuclear Factor NF Kappa B p65 Subunit, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B Cells 3, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-cells 3, p65, p65 NF kappaB, p65 NFkB, RELA, Transcription Factor p65, V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B Cells 3 (p65)), V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A, V Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian), V Rel Reticuloendotheliosis Viral Oncogene Homolog A, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B Cells 3, p65, V-rel Reticuloendotheliosis Viral Oncogene Homolog A) 100ug
