84-3433-37 KIN, NT (BTCD, KIN17, Binding to Curved DNA, Antigenic Determinant of RecA Protein (Mouse) Homolog, KIN, Antigenic Determinant of RecA Protein Homolog, Antigenic Determinant Of Reca, Mouse, Homolog Of) 100ug 303422
84-3433-37 KIN, NT (BTCD, KIN17, Binding to Curved DNA, Antigenic Determinant of RecA Protein (Mouse) Homolog, KIN, Antigenic Determinant of RecA Protein Homolog, Antigenic Determinant Of Reca, Mouse, Homolog Of) 100ug 303422
DNA/RNA-binding protein KIN17, also known as BTCD or KIN17 is a protein that in humans is encoded by the KIN gene.
This gene is mapped to 10p14.
The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle.
Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage.
Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.
Alternative splicing of this gene results in multiple transcript variants.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes human KIN. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa48-64, ESHQRQLLLASENPQQF, from human KIN at N-terminus, identical to the related mouse and rat sequences.