Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene.
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.
It is mapped to 11p14.1.
KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.
KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
This gene has been shown to interact with DLG4, KCNA2 and DLG1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human Kv1.4. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa329-344, LPEFRDDRDLVMALSA, from the middle region of human Kv1.4, different from the related mouse and rat sequences by 1aa.
Shelf Life：1year
Swiss Prot Number：P22459
EU Commodity Code：30021010
商品名：KCNA4 (Kv1.4, Voltage Gated K+ Channel HuKII, Cardiac Potassium Channel, Fetal Skeletal Muscle Potassium Channel, HBK 4, HBK4, HK 1, HK1, HPCN 2, HPCN2, HUK II, HUKII, KCNA 4, KCNA 8, KCNA4_HUMAN, KCNA4L, KCNA8, Kv1.4, PCN 2, PCN2, Potassium Channel 2, Potassium Channel KCNA4, Potassium Channel Protein, Potassium Voltage Gated Channel Shaker Related Subfamily Member 4, Potassium Voltage Gated Channel Subfamily A Member 4, Potassium Voltage-gated Channel Shaker-related Subfamily Member 4-like, Potassium Voltage-gated Channel Subfamily A Member 4, Rapidly Inactivating Potassium Channel, Shaker Related Potassium Channel Kv1.4, Shaker-related Potassium Channel Kv1.4, Type A Potassium Channel, Voltage Gated Potassium Channel HBK4, Voltage Gated Potassium Channel HK1, Voltage Gated Potassium Channel Subunit Kv1.4, Voltage-gated K(+) Channel HuKII, Voltage-gated Potassium Channel, Voltage-gated Potassium Channel HBK4, Voltage-gated Potassium Channel HK1, Voltage-gated Potassium Channel Protein Kv1.4, Voltage-gated Potassium Channel Subunit Kv1.4) 100ug
