Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene.
This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.
Kallikreins are a subgroup of serine proteases having diverse physiological functions.
Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
In particular, they may serve as biomarkers for both prostate cancer and breast cancer.
It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human Kallikrein 4.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human Kallikrein 4 expressed in E. coli. (Position: I31-S254).
