Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene.
This gene is mapped to 12q13.2.
The protein encoded by this gene belongs to the integrin alpha chain family.
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.
This protein functions as a receptor for the basement membrane protein laminin-1.
It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis.
Defects in this gene are associated with congenital myopathy.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human ITGA7. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa1123-1139, HAVKIPREDRQQFKEEK, from human ITGA7 at C-terminus, identical to the related mouse sequence, and different from the related rat sequence by 1aa.
