Integrin alpha-5, also known as FNRA or VLA5A, is a protein that in humans is encoded by the ITGA5 gene.
The product of this gene belongs to the integrin alpha chain family.
Integrins are integral membrane proteins composed of an alpha chain and a beta chain.
This gene encodes the integrin alpha 5 chain.
Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor.
In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes human Integrin alpha 5. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant protein corresponding to human Integrin alpha 5 expressed in E. coli. (Position: E787-E992). Species sequence homology: mouse (86%)
Shelf Life:1year
Swiss Prot Number:P08648
EU Commodity Code:30021010
商品名:Integrin alpha 5 (CD49 Antigen-like Family Member E, CD49e, Fibronectin Receptor alpha, Fibronectin Receptor Subunit alpha, Fibronectin Receptor, alpha Subunit, FNRA, Integrin alpha 5 (Fibronectin Receptor alpha), Integrin alpha-5, Integrin alpha-5 Light Chain, Integrin alpha-F, Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide), ITA5_HUMAN, ITGA 5, ITGA5, Very Late Activation Protein 5 alpha, Very Late Activation Protein 5, alpha Subunit, VLA-5, VLA5, VLA5A) 100ug