IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene.
IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease.
The IL-13 gene is mapped to 5q23-q31.
IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ra) and at least one of two known IL-13-specific binding chains.
This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes rat IL13.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Rt
Immunogen:Recombinant protein corresponding to rat IL13 expressed in E. coli. (Position: P22-H131). Species sequence homology: human (62%) and mouse (76%)