84-3433-05 IKK beta, CT (I kappa B Kinase 2, I kappa B Kinase beta, I-kappa-B Kinase 2, I-kappa-B-kinase beta, IkBKB, IKK 2, IKK B, IKK beta, IKK-B, IKK-beta, IKK2, IKKB, IKKB_HUMAN, Inhibitor of kappa Light Chain Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase beta, Inhibitor of kappa Light Poly ... 303381
84-3433-05 IKK beta, CT (I kappa B Kinase 2, I kappa B Kinase beta, I-kappa-B Kinase 2, I-kappa-B-kinase beta, IkBKB, IKK 2, IKK B, IKK beta, IKK-B, IKK-beta, IKK2, IKKB, IKKB_HUMAN, Inhibitor of kappa Light Chain Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase beta, Inhibitor of kappa Light Poly ... 303381
IKBKB (Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta), also known as IKKB or NFKBIKB , is a protein that in humans is encoded by the IKBKB gene.
Shindo et al.
(1998) mapped the IKBKB gene to chromosome 8p12-p11 by FISH.
Mercurio et al.
(1997) found that mutations in IKK2 had a more pronounced effect upon NFKB activation than did comparable mutations in IKK1.
Yin et al.
(1998) tested the activity of various anti inflammatory agents on the IKK complex.
They demonstrated that aspirin and sodium salicylate specifically inhibit IKK-beta activity in vitro and in vivo by binding to IKK-beta to reduce ATP binding.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.5ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human IKK beta. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa588-604, QEMVRLLLQAIQSFEKK, from human IKK beta at C-terminus, identical to the related mouse sequence, and different from the related rat sequence by 1aa.
Shelf Life：1year
Swiss Prot Number：O14920
EU Commodity Code：30021010
商品名：IKK beta, CT (I kappa B Kinase 2, I kappa B Kinase beta, I-kappa-B Kinase 2, I-kappa-B-kinase beta, IkBKB, IKK 2, IKK B, IKK beta, IKK-B, IKK-beta, IKK2, IKKB, IKKB_HUMAN, Inhibitor of kappa Light Chain Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase beta, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase beta, Inhibitor of Nuclear Factor kappa B Kinase beta Subunit, Inhibitor of Nuclear Factor kappa B Kinase Subunit beta, Inhibitor of Nuclear Factor kappa-B Kinase Subunit beta, NFKBIKB, Nuclear Factor NF kappa B Inhibitor Kinase beta, Nuclear Factor NF-kappa-B Inhibitor Kinase beta, Nuclear Factor of kappa Light Chain Gene Enhancer in B Cells Inhibitor) 100ug
