84-3432-72　GRIN2C (NMDAR2C, GluN2C, Glutamate [NMDA] Receptor Subunit epsilon-3, Glutamate Receptor Ionotropic N Methyl D Aspartate 2C, Glutamate Receptor Ionotropic, NMDA 2C, Glutamate Receptor, Ionotropic, N Methyl D Aspartate 2C, Grin2c, N Methyl D Aspartate Receptor Channel Subunit Epsilon 3, N Methyl D Aspartate Receptor Subtype 2C, N Methyl D Aspartate Receptor Subunit 2C, N-methyl D-aspartate Rece ...　303346

特徴

• NMDAR2C, known as GRIN2C, is mapped to 17q25.1.
• Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene.
• NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development.
• The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition.
• Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia.
• Alternative splicing results in multiple transcript variants.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.