FOXP3 (forkhead box P3) is a protein involved in immune system responses.
The human FOXP3 genes contain 11 coding exons.
Exon-intron boundaries are identical across the coding regions of the mouse and human genes.
By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome (specifically, Xp11.23).
A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells.
While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 0.5-1ug/ml, boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 0.2mg Na2HPO4, 5mg BSA, 0.9mg sodium chloride, 0.05mg sodium azide. Reconstitute with 200ul sterile dH2O to 0.5mg/ml.
Specificity：Recognizes human FOXP3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human FOXP3 expressed in E. coli. (Position: H101-P431). Species sequence homology: mouse (88%)
