84-3432-27　Eotaxin (C-C Motif Chemokine 11, CCL 11, CCL11, Chemokine (C-C Motif) Ligand 11, Chemokine C C Motif Ligand 11, Chemokine CC Motif Ligand 11, Chemokine Ligand 11, Eosinophil Chemotactic Protein, Eotaxin-1, SCYA 11, SCYA11, Small Inducible Cytokine A11, Small Inducible Cytokine Subfamily A (Cys Cys) Member 11, Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (Eotaxin), Small Inducible ...　303295

特徴

• CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes.
• The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues.
• CCL11 is a small cytokine belonging to the CC chemokine family.
• It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
• The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.