Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family.
The gene was assigned to human chromosome 5q13.2.
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II- mediated RNA transcription.
CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex.
It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity:Recognizes human Cdk7.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to human Cdk7 expressed in E.coli. (Position: D31-F346). Species sequence homology: mouse (95%) and rat (96%)