84-3431-40 CCL4 (MIP 1 beta, Secreted Protein G 26, ACT 2, ACT-2, ACT2, C C Motif Chemokine 4, C C Motif Chemokine 4 Like, CC Chemokine Ligand 4, CC Chemokine Ligand 4L1d2, CC Chemokine Ligand 4L2, Ccl4l 1, CCL4L, CCL4L1, Chemokine (C C Motif) Ligand 4, Chemokine (C C Motif) Ligand 4 Like 1, Chemokine (C C Motif) Ligand 4 Like 1, Telomeric, Chemokine (C C Motif) Ligand 4 Like 2, Chemokine CC Motif Ligand ... 303195
84-3431-40 CCL4 (MIP 1 beta, Secreted Protein G 26, ACT 2, ACT-2, ACT2, C C Motif Chemokine 4, C C Motif Chemokine 4 Like, CC Chemokine Ligand 4, CC Chemokine Ligand 4L1d2, CC Chemokine Ligand 4L2, Ccl4l 1, CCL4L, CCL4L1, Chemokine (C C Motif) Ligand 4, Chemokine (C C Motif) Ligand 4 Like 1, Chemokine (C C Motif) Ligand 4 Like 1, Telomeric, Chemokine (C C Motif) Ligand 4 Like 2, Chemokine CC Motif Ligand ... 303195
Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene.
By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23.
It is a CC chemokine with specificity for CCR5 receptors.
It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells.
CCL4 is a major HIV-suppressive factor produced by CD8+ T cells.
Performing-low memory CD8+ T cells that normally synthesize CCL4.
Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist.
MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes rat CCL4.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to rat CCL4 expressed in E. coli. (Position: A24-N92). Species sequence homology: human (80%) and mouse (86%)
Shelf Life：1year
Swiss Prot Number：P50230
EU Commodity Code：30021010
商品名：CCL4 (MIP 1 beta, Secreted Protein G 26, ACT 2, ACT-2, ACT2, C C Motif Chemokine 4, C C Motif Chemokine 4 Like, CC Chemokine Ligand 4, CC Chemokine Ligand 4L1d2, CC Chemokine Ligand 4L2, Ccl4l 1, CCL4L, CCL4L1, Chemokine (C C Motif) Ligand 4, Chemokine (C C Motif) Ligand 4 Like 1, Chemokine (C C Motif) Ligand 4 Like 1, Telomeric, Chemokine (C C Motif) Ligand 4 Like 2, Chemokine CC Motif Ligand 4, G 26, G 26 T Lymphocyte Secreted Protein, G-26 T-lymphocyte-secreted Protein, HC21, LAG 1, LAG-1, LAG1, Lymphocyte Activation Gene 1, Lymphocyte Activation Gene 1 Protein, Macrophage Inflammatory Protein 1 beta, Macrophage Inflammatory Protein 1-beta, Macrophage Inflammatory Protein 1b2, MIP 1 beta, MIP-1-beta, MIP-1-beta(1-69), MIP-1-beta (3-69), MIP1 beta, MIP1B, MIP1B1, Monocyte Adherence Induced Protein 5 alpha, PAT 744, Protein H400, SCYA2, SCYA4, SCYA4L, Secreted Protein G 26, Secreted Protein G26, SIS gamma, SIS-gamma, Small Inducible Cytokine A4 (Homologous to Mouse Mip 1b), Small Inducible Cytokine A4, Small-inducible Cytokine A4, T Cell Activation Protein 2, T-cell Activation Protein 2) 100ug
