84-3431-38　CCL18 (Alternative Macrophage Activation Associated CC Chemokine 1, Alternative Macrophage Activation-associated CC Chemokine 1, AMAC-1, AMAC1, CC Chemokine PARC, CCL18 (4-69), CCL18_HUMAN, CKb7, DC-CK1, DCCK1, Dendritic Cell Chemokine 1, Macrophage Inflammatory Protein 4, MIP-4, MIP4, PARC, Pulmonary and Activation Regulated Chemokine, Pulmonary and Activation-regulated Chemokine, SCYA18, Sma ...　303193

特徴

• Macrophage Inflammatory Protein 4, also known as CCL18, is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine).
• CCL18 is ~60% identical in aa sequence to CCL3.
• By analysis of a previously mapped CCL18 from 17q11.2, it is determined that the PARC gene is located within 1 of the 2 clusters of CC chemokine genes in this region.
• It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes.
• Beside, CCL18 recruits Th2 cells and basophils and may play a predominant role in allergic asthma.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.1-0.5ug/mlWestern Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.