Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene.
It is mapped to 3p21.1.
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression.
Alpha-1D subunit can mediate DHP-sensitive, high voltage-activated, long-lasting calcium channel activity.
CACNA1D can form L-type calcium channels with negative activation thresholds which is essential for normal auditory function and controling of cardiac pacemaker activity.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human CaV1.3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa2146-2161, RDEEDLADEMICITTL, from human CaV1.3 at C-terminus, different from the related mouse and rat sequences by 1aa.
Shelf Life：1year
Swiss Prot Number：Q01668
EU Commodity Code：30021010
商品名：CaV1.3, CT (Alpha-1 Polypeptide, CAC1D_HUMAN, CACH3, CACN4, CACNA 1D, CACNA1D, CACNL1A2, Calcium Channel, Calcium Channel L Type alpha 1 Polypeptide Isoform 2, Calcium Channel Neuroendocrine/Brain Type alpha 1 Subunit, Calcium Channel Voltage Dependent L Type alpha 1, Calcium Channel Voltage Dependent L Type alpha 1D Subunit, Cav1.3, CCHL1A2, Isoform 2, L Type, PASNA, SANDD, Voltage Dependent L Type Calcium Channel Subunit alpha 1D, Voltage Gated Calcium Channel alpha 1 Subunit, Voltage Gated Calcium Channel alpha Subunit Cav1.3, Voltage Gated Calcium Channel Subunit alpha Cav1.3, Voltage-dependent L-type Calcium Channel Subunit alpha-1D, Voltage-gated Calcium Channel Subunit alpha Cav1.3) 100ug
