84-3431-33　CaV1.3 (Alpha-1 Polypeptide, CAC1D_HUMAN, CACH3, CACN4, CACNA 1D, CACNA1D, CACNL1A2, Calcium Channel, Calcium Channel L Type alpha 1 Polypeptide Isoform 2, Calcium Channel Neuroendocrine/Brain Type alpha 1 Subunit, Calcium Channel Voltage Dependent L Type alpha 1, Calcium Channel Voltage Dependent L Type alpha 1D Subunit, Cav1.3, CCHL1A2, Isoform 2, L Type, PASNA, SANDD, Voltage Dependent L Ty ...　303188

特徴

• CACNA1D is also known as PASNA, SANDD or Cav1.3.
• Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression.
• Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits.
• The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity.
• The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S.
• This gene encodes the alpha-1D subunit.
• Several transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.