Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene.
This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3.
CADM1 functions as a homophilic cell adhesion molecule at the synapse.
Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly.
Conversely, expression of full-length CADM1 in nonneuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties.
CADM1 has been shown to interact with EPB41L3.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute with 200ul sterile dH2O to 0.5mg/ml.
Specificity：Recognizes human SynCAM. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa73-92, VIQLLNPNRQTIYFRDFRPL, from human SynCAM at N-terminus, identical to the related mouse and rat sequences.
