Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1.
Angiopoietins are proteins with important roles in vascular development and angiogenesis.
All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor.
Angiopoietin 1 is mapped to 8q23.1.
The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation.
It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.
The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Specificity：Recognizes human Angiopoietin 1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human Angiopoietin 1 expressed in E. coli. (Position: H16-N350). Species sequence homology: mouse and rat (96%)
