84-3430-43　ABCB4 (ABC 21, ABC B4, ABC21, ABCB 4, Abcb4, ABCB4 Protein, ATP Binding Cassette Sub Family B MDR/TAP Member 4, ATP Binding Cassette Sub Family B Member 4, ATP-binding Cassette Sub-family B Member 4, MDR 3, MDR2, MDR2/3, MDR3, MDR3 P Glycoprotein, MDR3 P Gp, MDR3_HUMAN, Multidrug Resistance Protein 3, Multiple Drug Resistance 3, P Glycoprotein 3, P-glycoprotein 3, PFIC 3, PFIC3, PGY 3, PGY3) 100ug　303087

特徴

• Adenosine triphosphate-binding cassette subfamily B, member 4 (ABCB4), also called MDR3, is a protein that in humans is encoded by the ABCB4 gene.
• The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
• The ABCB4 gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains.
• ABCB4 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions
• Immunohistochemistry (paraffin): 0.5-1ug/ml, boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.