84-3429-22 Sox17 (Transcription Factor SOX-17, Sox17, Sox-17) 200ul 302760
特徴
- Acts as transcription regulator that binds target promoter DNA and bends the DNA.
- Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'.
- Modulates transcriptional regulation via WNT3A.
- Inhibits Wnt signaling.
- Promotes degradation of activated CTNNB1.
- Plays a key role in the regulation of embryonic development.
- Required for normal looping of the embryonic heart tube.
- Required for normal development of the definitive gut endoderm.
- Probable transcriptional activator in the premeiotic germ cells.
- Isoform 2 (T-SOX17) shows no DNA-binding activity.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：200ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein A affinity chromatography.
- Form：Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity：Recognizes Sox17. Species Crossreactivity: human, mouse
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mo
- Immunogen：KLH conjugated synthetic peptide corresponding to aa376-409 at the C-terminal region of human (Mouse) Sox17.
- Shelf Life：1year
- Swiss Prot Number：Q61473
- EU Commodity Code：30021010
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