84-3423-72　KiSS-1 amide (Kisspeptin-10, Metastin amide) 50ul　302028

特徴

• This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity.
• The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas.
• Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization.
• A polymorphism in the terminal exon of this mRNA results in two protein isoforms.
• An adenosine present at the polymorphic site represents the third position in a stop codon.
• When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.
• [provided by RefSeq]
• Applications:Suitable for use in Indirect ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Indirect ELISA: 1:6400Western Blot: 1:500-1000Immunohistochemistry: 1:1000Immunohistochemistry(ABC): 1:500-1000Optimal dilutions to be determined by the researcher.
• Sequence:Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.