84-3423-71　KISS-1 (Metastin) 50ul　302027

特徴

• This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity.
• The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas.
• Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization.
• A polymorphism in the terminal exon of this mRNA results in two protein isoforms.
• An adenosine present at the polymorphic site represents the third position in a stop codon.
• When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.
• [provided by RefSeq]
• Applications:Suitable for use in Direct ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Direct ELISA: 1:3200Immunohistochemistry: 1:500Optimal dilutions to be determined by the researcher.
• Sequence:Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser -Arg-NH2.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.