Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of tau protein.
Furthermore, these accumulated tau proteins all display an abnormal phosphorylation pattern that may be disease specific.
As an example, Amyotrophic lateral sclerosis (ALS, also referred to as Charcot’s disease or Lou Gehrig’s disease) is the most common form of progressive motor neuron disease in North America.
ALS gradually disables the patient’s voluntary motor muscle control until it becomes fatal.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:10,000Immunohistochemistry: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, pH 7.4. No preservative added. Reconstitute with 50ul sterile ddH2O.
Specificity：Recognizes human Tau at Ser 208/210 phosphorylation site.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human Tau phosphorylated at Ser 208 and Ser 210
