P190RhoGAP, also known as GRLF1 (glucocorticoid receptor DNA binding factor 1) is a Rho family GTPase-activating protein that was identified as a protein that associates with p120RasGAP.
P190RhoGAP is a multidomain protein that plays crucial role in regulating actin cytoskeletal rearrangements in axonal pathfinding and stability and in response to growth factor stimulation, integrin engagement, and v-Src transformation.
Recently, it has been suggested that p190RhoGAP has also a role in regulating cell proliferation.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Ascites
Purity：Ascites
Form：Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
Specificity：Recognizes human P190RhoGAP.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human P190RhoGAP (catalytic domain fragment of 82kD)
