84-3422-88 Huntingtin-Interacting Protein 1-Related (HIP1R) 100ul 301674
特徴
- HIP1R (huntingtin interacting protein 1 related) was first cloned based on its sequence similarity with HIP1 (Huntingtin Interacting Protein 1).
- HIP1 binds to normal huntingtin but this interaction is lost in Huntington’s disease (HD).
- HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes.
- HIP1R colocalizes with and binds to actin and this interaction may link the endocytic machinery to the actin cytoskeletal dynamic processes.
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:50-1:250Western Blot: 1:500-1:2500Optimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
- Reconstitute with sterile ddH2O.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a lyophilized powder in PBS, pH 7.4, glycerol. Reconstitute with 100ul sterile ddH2O.
- Specificity：Recognizes the C-terminal portion of human HIP1R. Species Crossreactivity: rat
- Isotype：IgG1
- Calc Applications Abbrev：IF WB
- Calc Crossreactivity：Hu Rt
- Immunogen：Peptide corresponding to human HIP1R at C-terminal.
- Shelf Life：1year
- Swiss Prot Number：O75146
- EU Commodity Code：30021010
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