Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin.
HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD.
HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes.
HIP1 expression levels are altered in several types of cancer.
Applications:Suitable for use in Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:10-1:100Western Blot: 1:500-1:2500Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, pH 7.4, glycerol. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes human HIP1. Species Crossreactivity: rat
Isotype：IgG1
Calc Applications Abbrev：IF WB
Calc Crossreactivity：Hu Rt
Immunogen：Peptide corresponding to human HIP1 at C-terminal.
