Chromogranin-A is a secreted protein known as a “prohormone” which is found in endocrine cells and neurons and may be released upon stimulation.
It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells.
Chromogranin-A is used as a biomarker in patients with neuroendocrine tumors.
Recent publications show that incomplete processing of Chromogranin-A may be linked to diabetic retinopathy.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Ascites
Purity：Ascites
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes human Chromogranin-A. Species Crossreactivity: Mammals
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Ma
Immunogen：Peptide corresponding to aa4-16 from human Chromogranin-A at N-terminal.
