A large, cytokine-responsive IkappaB kinase (IKK) complex contains 2 subunits, IKK-alpha and IKK-beta, which are protein kinases whose function is needed for NF-kappaB activation by pro-inflammatory stimuli.
IKK is composed of similar amounts of IKK-alpha, and IKK-beta, which are differentially processed forms of a third subunit, IKK-gamma.
IKK-gamma interacts preferentially with IKK-beta and is required for the activation of the IKK complex.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes IKK-gamma.
Isotype:IgG
Calc Applications Abbrev:WB
Immunogen:Residues aa2-13 [NRHLWKSQLCEM] of IKK-gamma.