The 9D2 antigen isolated from senile plaque amyloid was identified as collagen-like Alzheimer amyloid plaque component (CLAC), and its precursor as CLACP/collagen type XXV.
Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bind to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes the NC2-2 region of human CLAC-P. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Residues aa155-169 [KGEQGDQGPRMVFPK] at the NC2-2 region of human CLAC-P.
