84-3418-34　［取扱停止］DARC (CT) (Duffy Antigen/Chemokine Receptor, Duffy Antigen/Chemokine Receptor, Fy Glycoprotein D, GpFy, Cell Adhesion Molecule 3, CADM3, Plasmodium Vivax Receptor,CCBP1, CD234, CD234 antigen, Dfy, GpFy, Plasmodium vivax receptor) (MaxLight 750) 100ul　D1065-50H-ML750

特徴

• MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000.
• CD234 is a non-specific receptor for a number of cytokines including IL-8, GRO, RANTES, MCP-1 and TARC.
• CD234 also functions as the receptor for the malaria parasites Plasmodium vivax and P.
• knowlesi.
• CD234 is also responsible for the Duffy blood group system where a substitution at position 42 of either Gly-42 or Asp-42 results in Fy(A) or Fy(B).
• CD234 is present in adult kidney, adult spleen, bone marrow and fetal liver.
• In particular, it is expressed along post capillary venules throughout the body, except in the adult liver.
• Erythroid cells and post capillary venule endothelium are the principle tissues expressing duffy.
• Fy(-A-B) individuals do not express duffy in the bone marrow, however they do, in postcapillary venule endothelium.
• It has been demonstrated that CD234 exists in multiple isoforms.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications have not tested.
• Recommended Dilution:Immunohistochemistry: Paraffin.
• Requires antigen retrieval using heat treatment prior to staining paraffin sections.
• Sodium citrate buffer pH 6.0 is recommended.
• Optimal dilutions to be determined by the researcher.
• Immunohistochemistry Positive Control Tissue:Mouse brain
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™750 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.