84-3406-49　［取扱停止］Ring Finger Protein 34 (RNF34, Caspase Regulator CARP1, Caspases 8 and 10-associated RING Finger Protein 1, CARP-1, FLJ21786, FYVE-RING Finger Protein Momo, hRFI, Human RING Finger Homologous to Inhibitor of Apoptosis Protein hRFI, RFI, RIFF, Ring Finger Protein RIFF) (MaxLight 405) 100ul　R2031-88B-ML405

特徴

• MaxLight™405 is a new Violet photostable dye conjugate comparable to Alexa Fluor® 405, PacificBlue™, Brilliant™ Violet 421 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (400nm); Emission (423nm); Extinction Coefficient 32,000.
• Ring Finger is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL.
• It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation.
• hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm.
• hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.
• Applications:Suitable for use in FLISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:FLISA: 1:800-1:4000Western Blot: 1:100-1:600.
• Detects a band at ~42kDOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™405 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.