Human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), is a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway.
IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R.
Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).
Applications:Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence.
Other applications not tested.
Recommended Dilution:ELISA: 1:50,000Immunohistochemistry (Paraffin): 1:50Immunofluorescence: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes an epitope within the N-terminal region of human Interleukin-22 Receptor.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa42-70, DSGPEGTPDTVYSIEYKTYGERDWVAKKG, within the N-terminal region of human IL-22 Receptor.
