84-3397-79 DcR3, NT (TR6, Decoy Receptor 3, TNFRSF6B, TR6, M68) (HRP) 100ul D1500-25M-HRP
特徴
- Decoy Receptor 3 is a 33kD member of the tumor necrosis factor receptor superfamily.
- DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis.
- DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung.
- It may also be found in fetal lung, brain and liver.
- It is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry (Paraffin): Requires heat induced epitope retrieval.
- Sodium citrate buffer pH 6.0 is recommended for this purpose
- Optimal dilutions to be determined by the researcher.
- Positive Control:WB: Human heart lysate
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Note: Applications are based on unconjugated antibody.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Highly Purified
- Purity:Purified by Ion Exchange chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
- Specificity:Recognizes the N-terminus of human DcR3 at ~33kD. Species Crossreactivity: mouse and rat.
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to amino acids near the N-terminus of human DcR3 precursor.
- Shelf Life:1year
- Swiss Prot Number:O95407
- EU Commodity Code:30021010
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